Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05IQX
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| Former ID |
DCL000493
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| Drug Name |
Belimumab
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| Synonyms |
Belimumab (USAN); LymphoStat-B; LymphoStat-B (TN)
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| Drug Type |
Antibody
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| Indication | Systemic lupus erythematosus [ICD-11: 4A40.0; ICD-9: 710] | Approved | [1], [2] | |
| Company |
GSK
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| PubChem Substance ID | ||||
| ADReCS Drug ID | BADD_D00224 | |||
| SuperDrug ATC ID |
L04AA26
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | B-cell-activating factor (TNFSF13B) | Target Info | . | [3] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| NF-kappa B signaling pathway | ||||
| Intestinal immune network for IgA production | ||||
| Rheumatoid arthritis | ||||
| Reactome | TNFR2 non-canonical NF-kB pathway | |||
| TNFs bind their physiological receptors | ||||
| TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | ||||
| WikiPathways | Spinal Cord Injury | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6887). | |||
| REF 2 | New developments in immunosuppressive therapy for heart transplantation. Expert Opin Emerg Drugs. 2009 Mar;14(1):1-21. | |||
| REF 3 | Clinical pipeline report, company report or official report of GlaxoSmithKline (2009). | |||
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