Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05FOV
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| Former ID |
DIB018570
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| Drug Name |
2-oleoyl glycerol
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| Synonyms |
2-monoolein; 2-oleoyl-glycerol; 2-oleoylglycerol (2OG)
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C21H40O4
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| Canonical SMILES |
CCCCCCCCC=CCCCCCCCC(=O)OC(CO)CO
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| InChI |
1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-20(18-22)19-23/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-
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| InChIKey |
UPWGQKDVAURUGE-KTKRTIGZSA-N
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| CAS Number |
CAS 3443-84-3
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:73990
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glucose-dependent insulinotropic receptor (GPR119) | Target Info | Agonist | [2] |
| KEGG Pathway | cAMP signaling pathway | |||
| Insulin secretion | ||||
| WikiPathways | Incretin Synthesis, Secretion, and Inactivation | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5112). | |||
| REF 2 | 2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans. J Clin Endocrinol Metab. 2011 Sep;96(9):E1409-17. | |||
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