Drug Information
Drug General Information | Top | |||
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Drug ID |
D05FKU
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Drug Name |
ETC-1922159
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Synonyms |
Etc-159; ETC-159; UNII-5L854240DQ; 1638250-96-0; CHEMBL3633802; 5L854240DQ; SCHEMBL17626176; MolPort-044-728-903; KS-00000TT9; BDBM50133866; ZINC175660737; AKOS030526630; CS-5162; 2-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(6-phenylpyridazin-3-yl)acetamide; HY-18988; 2-(1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-7-yl)-N-(6-phenylpyridazin-3-yl)acetamide
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Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C00-D48; ICD-9: 140-199, 210-229] | Phase 1 | [1] | |
Company |
Biomedical Sciences Institute SingaporeD3 (Drug Product and Development) Singapore
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Structure |
Download2D MOL |
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Formula |
C19H17N7O3
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Canonical SMILES |
CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC(=O)NC3=NN=C(C=C3)C4=CC=CC=C4
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InChI |
1S/C19H17N7O3/c1-24-17-16(18(28)25(2)19(24)29)26(11-20-17)10-15(27)21-14-9-8-13(22-23-14)12-6-4-3-5-7-12/h3-9,11H,10H2,1-2H3,(H,21,23,27)
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InChIKey |
QTRXIFVSTWXRJJ-UHFFFAOYSA-N
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CAS Number |
CAS 1638250-96-0
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Protein-serine O-palmitoleoyltransferase porcupine (PORCN) | Target Info | Inhibitor | [1] |
References | Top | |||
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REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) |
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