Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D05ETM
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| Former ID |
DNC000478
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| Drug Name |
CP-99,994
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| Synonyms |
CP-99994; CHEMBL441225; CP99994; CP 99994; (2S,3S)-N-(2-methoxybenzyl)-2-phenylpiperidin-3-amine; (2S,3S)-N-[(2-methoxyphenyl)methyl]-2-phenylpiperidin-3-amine; (2~{S},3~{S})-~{N}-[(2-methoxyphenyl)methyl]-2-phenyl-piperidin-3-amine; UNII-5KM4QA7RZC; 5KM4QA7RZC; AC1NSJX2; (2-Methoxy-benzyl)-(2-phenyl-piperidin-3-yl)-amine; SCHEMBL1282327; GTPL2102; DTQNEFOKTXXQKV-HKUYNNGSSA-N; ZINC22441784; BDBM50000041; AKOS027453648; NCGC00370844-01; Cis-3-(2-methoxybenzylamino)-2-phenylpiperidine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C19H24N2O
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| Canonical SMILES |
COC1=CC=CC=C1CNC2CCCNC2C3=CC=CC=C3
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| InChI |
1S/C19H24N2O/c1-22-18-12-6-5-10-16(18)14-21-17-11-7-13-20-19(17)15-8-3-2-4-9-15/h2-6,8-10,12,17,19-21H,7,11,13-14H2,1H3/t17-,19-/m0/s1
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| InChIKey |
DTQNEFOKTXXQKV-HKUYNNGSSA-N
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| CAS Number |
CAS 136982-36-0
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| SuperDrug ATC ID |
L01DB02
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| SuperDrug CAS ID |
cas=020830813
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Substance-P receptor (TACR1) | Target Info | Antagonist | [2] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Measles | ||||
| Panther Pathway | CCKR signaling map ST | |||
| Reactome | G alpha (q) signalling events | |||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| Spinal Cord Injury | ||||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2102). | |||
| REF 2 | Gabapentin and the neurokinin(1) receptor antagonist CI-1021 act synergistically in two rat models of neuropathic pain. J Pharmacol Exp Ther. 2002 Nov;303(2):730-5. | |||
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