Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05DXT
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| Former ID |
DIB016833
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| Drug Name |
XEN-D0103
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| Synonyms |
KCNA voltage-gated potassium channel-5 inhibitor (atrial fibrillation), Xention
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| Indication | Atrial fibrillation [ICD-11: BC81.3; ICD-10: I48] | Phase 1 | [1] | |
| Company |
Xention Ltd
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated potassium channel Kv1.5 (KCNA5) | Target Info | Inhibitor | [2] |
| Pathwhiz Pathway | Muscle/Heart Contraction | |||
| Reactome | Voltage gated Potassium channels | |||
| WikiPathways | Potassium Channels | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT02390258) Fed-Fasted, Single and Multiple Ascending Dose Trial of XEN-D0103. U.S. National Institutes of Health. | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 542). | |||
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