Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05DDN
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| Former ID |
DCL000835
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| Drug Name |
HCV-796
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| Synonyms |
Nesbuvir; Nesbuvir (USAN); 79Z
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| Drug Type |
Small molecular drug
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| Indication | Hepatitis C virus infection [ICD-11: 1E51.1; ICD-10: B18.2] | Discontinued in Phase 2 | [1] | |
| Company |
ViroPharma; Wyeth
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| Structure |
 |
Download2D MOL |
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| Formula |
C22H23FN2O5S
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| Canonical SMILES |
CNC(=O)C1=C(OC2=CC(=C(C=C21)C3CC3)N(CCO)S(=O)(=O)C)C4=CC=C(C=C4)F
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| InChI |
1S/C22H23FN2O5S/c1-24-22(27)20-17-11-16(13-3-4-13)18(25(9-10-26)31(2,28)29)12-19(17)30-21(20)14-5-7-15(23)8-6-14/h5-8,11-13,26H,3-4,9-10H2,1-2H3,(H,24,27)
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| InChIKey |
WTDWVLJJJOTABN-UHFFFAOYSA-N
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| CAS Number |
CAS 691852-58-1
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| PubChem Compound ID | ||||
| PubChem Substance ID |
16663606, 24464334, 24716663, 42703274, 57269517, 57269518, 79167686, 96025634, 99443709, 103746791, 134223834, 134339301, 134339626, 135252257, 137095430, 139725969, 152159606, 152258602, 160647436, 160968321, 170482427, 170482428, 174007343, 185990490, 198942728, 223436388, 224170262, 228617599, 247953675
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Hepatitis C virus RNA-directed RNA polymerase (HCV NS5B) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Emerging drugs for hepatitis C. Expert Opin Emerg Drugs. 2008 Mar;13(1):1-19. | |||
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