Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D05CRM
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| Former ID |
DNC010858
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| Drug Name |
AMG-9090
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| Synonyms |
AMG-9090; 118215-82-0; CHEMBL1086371; N-{2,2,2-trichloro-1-[(4-chlorophenyl)sulfanyl]ethyl}benzamide; N-(2,2,2-trichloro-1-((4-chlorophenyl)sulfanyl)ethyl)benzamide; AC1MLXZ1; SCHEMBL15159501; MolPort-002-804-203; BDBM50318455; AKOS001602233; MCULE-4762847116; NCGC00322013-01; BC600809; A-300; ST50981355; AB01317363-02; AF-962/31929042; N-(2,2,2-trichloro-1-(4-chlorophenylthio)ethyl)benzamide; N-[2,2,2-trichloro-1-(4-chlorophenyl)sulfanylethyl]benzamide; N-{2,2,2-trichloro-1-[(4-chlorophenyl)thio]ethyl}benzamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H11Cl4NOS
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| Canonical SMILES |
C1=CC=C(C=C1)C(=O)NC(C(Cl)(Cl)Cl)SC2=CC=C(C=C2)Cl
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| InChI |
1S/C15H11Cl4NOS/c16-11-6-8-12(9-7-11)22-14(15(17,18)19)20-13(21)10-4-2-1-3-5-10/h1-9,14H,(H,20,21)
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| InChIKey |
NOXDIPWNQOTUAB-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Transformation-sensitive protein p120 (TRPA1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Inflammatory mediator regulation of TRP channels | |||
| Reactome | TRP channels | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents. J Med Chem. 2010 Jul 22;53(14):5085-107. | |||
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