Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04XDT
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| Drug Name |
Delafloxacin Meglumine
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| Synonyms |
Baxdela
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| Drug Type |
Small molecular drug
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| Indication | Acute bacterial skin infection [ICD-11: 1C41] | Approved | [1] | |
| Skin infection [ICD-11: 1F28-1G0Z; ICD-10: L00-L99; ICD-9: 680-709] | Approved | [2] | ||
| Company |
Melinta Therapeutics
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| Structure |
 |
Download2D MOL
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| Formula |
C25H29ClF3N5O9
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| Canonical SMILES |
CNCC(C(C(C(CO)O)O)O)O.C1C(CN1C2=C(C=C3C(=C2Cl)N(C=C(C3=O)C(=O)O)C4=C(C=C(C(=N4)N)F)F)F)O
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| InChI |
1S/C18H12ClF3N4O4.C7H17NO5/c19-12-13-7(1-9(20)14(12)25-3-6(27)4-25)15(28)8(18(29)30)5-26(13)17-11(22)2-10(21)16(23)24-17;1-8-2-4(10)6(12)7(13)5(11)3-9/h1-2,5-6,27H,3-4H2,(H2,23,24)(H,29,30);4-13H,2-3H2,1H3/t;4-,5+,6+,7+/m.0/s1
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| InChIKey |
AHJGUEMIZPMAMR-WZTVWXICSA-N
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| CAS Number |
CAS 352458-37-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Plasmodium DNA gyrase (Malaria gyrase) | Target Info | Inhibitor | [2] |
| Staphylococcus Topoisomerase IV (Stap-coc parC) | Target Info | Inhibitor | [2] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2018 | |||
| REF 2 | 2017 FDA drug approvals.Nat Rev Drug Discov. 2018 Feb;17(2):81-85. | |||
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