Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04UYT
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| Former ID |
DIB004346
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| Drug Name |
CBLB-612
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| Synonyms |
Recombinant flagellin proteins (injectable, radiation induced bone marrow deficiency), Cleveland BioLabs; CBLB-600 series (injectable, radiation sickness), Cleveland BioLabs
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| Indication | Radiation syndrome [ICD-11: NF00; ICD-10: T66; ICD-9: 990] | Investigative | [1] | |
| Company |
Cleveland BioLabs Inc
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Toll-like receptor 2 (TLR2) | Target Info | Modulator | [1] |
| KEGG Pathway | Phagosome | |||
| PI3K-Akt signaling pathway | ||||
| Toll-like receptor signaling pathway | ||||
| Legionellosis | ||||
| Leishmaniasis | ||||
| Chagas disease (American trypanosomiasis) | ||||
| Malaria | ||||
| Toxoplasmosis | ||||
| Amoebiasis | ||||
| Tuberculosis | ||||
| Hepatitis B | ||||
| Measles | ||||
| Herpes simplex infection | ||||
| Proteoglycans in cancer | ||||
| Inflammatory bowel disease (IBD) | ||||
| Rheumatoid arthritis | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| TCR Signaling Pathway | ||||
| Panther Pathway | Toll receptor signaling pathway | |||
| Pathway Interaction Database | Endogenous TLR signaling | |||
| Reactome | Beta defensins | |||
| MyD88:Mal cascade initiated on plasma membrane | ||||
| Toll Like Receptor TLR6:TLR2 Cascade | ||||
| MyD88 deficiency (TLR2/4) | ||||
| IRAK4 deficiency (TLR2/4) | ||||
| WikiPathways | Toll-like receptor signaling pathway | |||
| IL1 and megakaryotyces in obesity | ||||
| Human Complement System | ||||
| Toll-Like Receptors Cascades | ||||
| MyD88:Mal cascade initiated on plasma membrane | ||||
| Defensins | ||||
| Regulation of toll-like receptor signaling pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1752). | |||
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