Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D04UXN
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| Drug Name |
YYDJCLCSBYCSCO-UHFFFAOYSA-N
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| Synonyms |
CHEMBL1080382; 6-[cyclohexyl(cyclopropylmethyl)amino]-N-(6-methyl-1H-indazol-5-yl)pyrimidine-4-carboxamide; 6-(cyclohexyl(cyclopropylmethyl)amino)-N-(6-methyl-1H-indazol-5-yl)pyrimidine-4-carboxamide; SCHEMBL3025879; YYDJCLCSBYCSCO-UHFFFAOYSA-N; BDBM50313353
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| Drug Type |
Small molecular drug
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| Structure |
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Download2D MOL |
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| Formula |
C23H28N6O
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| Canonical SMILES |
CC1=CC2=C(C=C1NC(=O)C3=CC(=NC=N3)N(CC4CC4)C5CCCCC5)C=NN2
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| InChI |
1S/C23H28N6O/c1-15-9-20-17(12-26-28-20)10-19(15)27-23(30)21-11-22(25-14-24-21)29(13-16-7-8-16)18-5-3-2-4-6-18/h9-12,14,16,18H,2-8,13H2,1H3,(H,26,28)(H,27,30)
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| InChIKey |
YYDJCLCSBYCSCO-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sphingosine-1-phosphate receptor 3 (S1PR3) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Sphingosine-1-phosphate receptor 3 (S1PR3) | Target's Patent Info | [1] | |
| KEGG Pathway | Sphingolipid signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Pathway Interaction Database | S1P3 pathway | |||
| Sphingosine 1-phosphate (S1P) pathway | ||||
| Reactome | G alpha (i) signalling events | |||
| Lysosphingolipid and LPA receptors | ||||
| WikiPathways | Signal Transduction of S1P Receptor | |||
| Small Ligand GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
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| REF 1 | 6-amino-pyrimidine-4-carboxamide derivatives and related compounds which bind to the sphingosine 1-phosphate (S1P) receptor for the treatment of multiple sclerosis. US9150519. | |||
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