Drug Information
Drug General Information | Top | |||
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Drug ID |
D04TVU
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Drug Name |
RU-5135
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Synonyms |
78774-26-2; R-5135
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C18H28N2O2
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Canonical SMILES |
CC12CCC(CC1CCC3C2C(=O)CC4(C3CC(=N4)N)C)O
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InChI |
1S/C18H28N2O2/c1-17-6-5-11(21)7-10(17)3-4-12-13-8-15(19)20-18(13,2)9-14(22)16(12)17/h10-13,16,21H,3-9H2,1-2H3,(H2,19,20)/t10-,11-,12+,13+,16-,17+,18+/m1/s1
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InChIKey |
LLAKESJIQFAQJA-NJYPJRCCSA-N
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CAS Number |
CAS 78774-26-2
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | GABA(A) receptor delta (GABRD) | Target Info | Modulator | [1] |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Retrograde endocannabinoid signaling | ||||
GABAergic synapse | ||||
Morphine addiction | ||||
Nicotine addiction |
References | Top | |||
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REF 1 | Complex interactions between the steroid derivative RU 5135 and the GABAA-receptor complex. Eur J Pharmacol. 1992 Oct 1;227(2):147-51. |
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