Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D04STF
|
|||
Former ID |
DNC010233
|
|||
Drug Name |
NSC-745798
|
|||
Synonyms |
NSC-745798; SCHEMBL2400890
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C22H14N2O2
|
|||
Canonical SMILES |
CC1=CC=C(C=C1)C2=NC3=C(N2)C=CC4=C3C(=O)C5=CC=CC=C5C4=O
|
|||
InChI |
1S/C22H14N2O2/c1-12-6-8-13(9-7-12)22-23-17-11-10-16-18(19(17)24-22)21(26)15-5-3-2-4-14(15)20(16)25/h2-11H,1H3,(H,23,24)
|
|||
InChIKey |
MRHQJLSJDVEZQP-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | TERT messenger RNA (TERT mRNA) | Target Info | Inhibitor | [1] |
KEGG Pathway | HTLV-I infection | |||
NetPath Pathway | IL2 Signaling Pathway | |||
Pathway Interaction Database | Validated targets of C-MYC transcriptional activation | |||
Regulation of Telomerase | ||||
IL2 signaling events mediated by PI3K | ||||
Regulation of nuclear beta catenin signaling and target gene transcription | ||||
HIF-1-alpha transcription factor network | ||||
Reactome | Formation of the beta-catenin:TCF transactivating complex | |||
WikiPathways | TGF beta Signaling Pathway | |||
miR-targeted genes in lymphocytes - TarBase | ||||
miR-targeted genes in epithelium - TarBase | ||||
Telomere Maintenance |
References | Top | |||
---|---|---|---|---|
REF 1 | Synthesis, cytotoxicity and human telomerase inhibition activities of a series of 1,2-heteroannelated anthraquinones and anthra[1,2-d]imidazole-6,1... Bioorg Med Chem. 2009 Nov 1;17(21):7418-28. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.