Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04SBX
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| Former ID |
DIB012395
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| Drug Name |
Temafloxacin
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| Synonyms |
Omniflox; Temabiotic; Temac; Temadie; Temaflox; Temafloxacin hydrochloride; A-62254; A-63004; T-30036; TA-167
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| Drug Type |
Small molecular drug
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| Indication | Bacterial infection [ICD-11: 1A00-1C4Z; ICD-10: A00-B99] | Withdrawn from market | [1] | |
| Company |
Abbott Laboratories
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| Structure |
 |
Download2D MOL |
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| Formula |
C21H18F3N3O3
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| Canonical SMILES |
CC1CN(CCN1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4=C(C=C(C=C4)F)F)F
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| InChI |
1S/C21H18F3N3O3/c1-11-9-26(5-4-25-11)19-8-18-13(7-16(19)24)20(28)14(21(29)30)10-27(18)17-3-2-12(22)6-15(17)23/h2-3,6-8,10-11,25H,4-5,9H2,1H3,(H,29,30)
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| InChIKey |
QKDHBVNJCZBTMR-UHFFFAOYSA-N
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| CAS Number |
CAS 108319-06-8
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:77796
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial DNA gyrase (Bact gyrase) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000542) | |||
| REF 2 | Mechanisms and frequency of resistance to temafloxacin. Am J Med. 1991 Dec 30;91(6A):27S-30S. | |||
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