Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04OXD
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| Former ID |
DIB014777
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| Drug Name |
Netivudine
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| Synonyms |
Zonavir; BW-882; BW-882C; 882-C-87; 882C
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| Drug Type |
Small molecular drug
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| Indication | Virus infection [ICD-11: 1A24-1D9Z] | Phase 3 | [1] | |
| Company |
Burroughs Wellcome Inc
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| Structure |
 |
Download2D MOL |
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| Formula |
C12H14N2O6
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| Canonical SMILES |
CC#CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O
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| InChI |
1S/C12H14N2O6/c1-2-3-6-4-14(12(19)13-10(6)18)11-9(17)8(16)7(5-15)20-11/h4,7-9,11,15-17H,5H2,1H3,(H,13,18,19)/t7-,8-,9+,11-/m1/s1
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| InChIKey |
QLOCVMVCRJOTTM-SDNRWEOFSA-N
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| CAS Number |
CAS 84558-93-0
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Herpes simplex virus DNA polymerase UL30 (HSV UL30) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00002315) A Comparison of 882C87 Versus Acyclovir in the Treatment of Herpes Zoster in Patients With Weakened Immune Systems. U.S. National Institutes of Health. | |||
| REF 2 | Current pharmacological approaches to the therapy of varicella zoster virus infections: a guide to treatment. Drugs. 1999 Feb;57(2):187-206. | |||
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