Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04ONP
|
|||
| Former ID |
DIB011610
|
|||
| Drug Name |
ALBIFYLLINE
|
|||
| Synonyms |
HWA-138; Albifylline; 1-(5-Hydroxy-5-methylhexyl)-3-methylxanthine
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Sepsis [ICD-11: 1G40-1G41; ICD-10: R57.2; ICD-9: 785.52] | Discontinued in Phase 1 | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C13H20N4O3
|
|||
| Canonical SMILES |
CC(C)(CCCCN1C(=O)C2=C(N=CN2)N(C1=O)C)O
|
|||
| InChI |
1S/C13H20N4O3/c1-13(2,20)6-4-5-7-17-11(18)9-10(15-8-14-9)16(3)12(17)19/h8,20H,4-7H2,1-3H3,(H,14,15)
|
|||
| InChIKey |
NWXULHNEYYFVMF-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 107767-55-5
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase (PDE) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003224) | |||
| REF 2 | Enhanced tumor necrosis factor suppression and cyclic adenosine monophosphate accumulation by combination of phosphodiesterase inhibitors and prostanoids. Eur J Immunol. 1995 Jan;25(1):147-53. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.