Drug Information
Drug General Information | Top | |||
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Drug ID |
D04LZJ
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Former ID |
DNC014556
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Drug Name |
(3-Amino-propyl)-phosphonic acid
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Synonyms |
3-Aminopropylphosphonic acid; 13138-33-5; (3-aminopropyl)phosphonic acid; Aminopropylphosphonate; 3-Aminopropylphosphonicacid; UNII-VM92T06VPB; (3-Amino-propyl)-phosphonic acid; Phosphonic acid, (3-aminopropyl)-; VM92T06VPB; CHEMBL286077; GSZQTIFGANBTNF-UHFFFAOYSA-N; GEO-00218; NSC-133832; 3-phosphonopropylamine; AK-33107; 3-Appn; (3-Aminopropyl)phosphonic acid, 97%; NSC 133832; Phosphate analogue, 8; PubChem10325; ACMC-1BXXY; AC1L3YTO; 3-aminopropyl-phosphonate; timtec-bb sbb004184; Lopac-A-7162; AC1Q6RQ7; SCHEMBL35883
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C3H10NO3P
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Canonical SMILES |
C(CN)CP(=O)(O)O
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InChI |
1S/C3H10NO3P/c4-2-1-3-8(5,6)7/h1-4H2,(H2,5,6,7)
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InChIKey |
GSZQTIFGANBTNF-UHFFFAOYSA-N
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CAS Number |
CAS 13138-33-5
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PubChem Compound ID | ||||
ChEBI ID |
CHEBI:142993
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Target and Pathway | Top | |||
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Target(s) | Gamma-aminobutyric acid B receptor (GABBR) | Target Info | Inhibitor | [1] |
KEGG Pathway | cAMP signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
GABAergic synapse | ||||
Estrogen signaling pathway | ||||
Morphine addiction | ||||
Reactome | Activation of G protein gated Potassium channels | |||
G alpha (i) signalling events | ||||
Class C/3 (Metabotropic glutamate/pheromone receptors) | ||||
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | ||||
WikiPathways | GPCRs, Class C Metabotropic glutamate, pheromone | |||
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
Potassium Channels | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | Phosphorus analogues of gamma-aminobutyric acid, a new class of anticonvulsants. J Med Chem. 1984 May;27(5):654-9. |
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