Drug Information
Drug General Information | Top | |||
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Drug ID |
D04LTV
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Former ID |
DNC010239
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Drug Name |
2,3-Dimethylnaphtho[2,3-f]quinoxaline-7,12-dione
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Synonyms |
2,3-Dimethylnaphtho[2,3-f]quinoxaline-7,12-dione; 89986-91-4; Naphtho[2,3-f]quinoxaline-7,12-dione, 2,3-dimethyl-; ACMC-20lsfz; SCHEMBL3505034; CHEMBL604342; CTK2I7956; DTXSID80658048
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C18H12N2O2
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Canonical SMILES |
CC1=C(N=C2C(=N1)C=CC3=C2C(=O)C4=CC=CC=C4C3=O)C
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InChI |
1S/C18H12N2O2/c1-9-10(2)20-16-14(19-9)8-7-13-15(16)18(22)12-6-4-3-5-11(12)17(13)21/h3-8H,1-2H3
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InChIKey |
WDHCRURNPCZZII-UHFFFAOYSA-N
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CAS Number |
CAS 89986-91-4
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | TERT messenger RNA (TERT mRNA) | Target Info | Inhibitor | [1] |
KEGG Pathway | HTLV-I infection | |||
NetPath Pathway | IL2 Signaling Pathway | |||
Pathway Interaction Database | Validated targets of C-MYC transcriptional activation | |||
Regulation of Telomerase | ||||
IL2 signaling events mediated by PI3K | ||||
Regulation of nuclear beta catenin signaling and target gene transcription | ||||
HIF-1-alpha transcription factor network | ||||
Reactome | Formation of the beta-catenin:TCF transactivating complex | |||
WikiPathways | TGF beta Signaling Pathway | |||
miR-targeted genes in lymphocytes - TarBase | ||||
miR-targeted genes in epithelium - TarBase | ||||
Telomere Maintenance |
References | Top | |||
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REF 1 | Synthesis, cytotoxicity and human telomerase inhibition activities of a series of 1,2-heteroannelated anthraquinones and anthra[1,2-d]imidazole-6,1... Bioorg Med Chem. 2009 Nov 1;17(21):7418-28. |
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