Drug Information
Drug General Information | Top | |||
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Drug ID |
D04KQT
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Former ID |
DIB019773
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Drug Name |
dodecyl-thiophosphate
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Synonyms |
Dodecyl-thiophosphate; Thiophosphoric acid dodecyl ester; CHEMBL191365; Phosphorothioic acid, O-dodecyl ester; SCHEMBL40052; GTPL6990; thiophosphoric acid o-dodecyl ester; BDBM50170860
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2] | |
Structure |
Download2D MOL |
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Formula |
C12H27O3PS
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Canonical SMILES |
CCCCCCCCCCCCOP(=S)(O)O
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InChI |
1S/C12H27O3PS/c1-2-3-4-5-6-7-8-9-10-11-12-15-16(13,14)17/h2-12H2,1H3,(H2,13,14,17)
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InChIKey |
ISWBBUXCFWZBKC-UHFFFAOYSA-N
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CAS Number |
CAS 710277-85-3
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Lysophosphatidate-3 receptor (LPAR3) | Target Info | Antagonist | [2] |
Lysophosphatidic acid receptor 1 (LPAR1) | Target Info | Inhibitor | [2] | |
Lysophosphatidic acid receptor 2 (LPAR2) | Target Info | Agonist | [2] | |
KEGG Pathway | Rap1 signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
PI3K-Akt signaling pathway | ||||
Pathways in cancer | ||||
Gap junction | ||||
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
Pathway Interaction Database | LPA receptor mediated events | |||
Reactome | G alpha (q) signalling events | |||
G alpha (i) signalling events | ||||
Lysosphingolipid and LPA receptors | ||||
WikiPathways | Gastrin-CREB signalling pathway via PKC and MAPK | |||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
Myometrial Relaxation and Contraction Pathways | ||||
Small Ligand GPCRs |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6990). | |||
REF 2 | Synthesis, structure-activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, activ... J Med Chem. 2005 Jul 28;48(15):4919-30. |
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