Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04GYR
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| Drug Name |
PMID28870136-Compound-61
|
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| Drug Type |
Small molecular drug
|
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| Company |
ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC
|
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| Structure |
 |
Download2D MOL |
||
| Formula |
C22H22N4O
|
|||
| Canonical SMILES |
CC(C)(C)CN1C(=O)C=CC(=N1)C2=C3C=CC=CN3N=C2C4=CC=CC=C4
|
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| InChI |
1S/C22H22N4O/c1-22(2,3)15-26-19(27)13-12-17(23-26)20-18-11-7-8-14-25(18)24-21(20)16-9-5-4-6-10-16/h4-14H,15H2,1-3H3
|
|||
| InChIKey |
XGZUBYNARGEPRB-UHFFFAOYSA-N
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Ecto-5'-nucleotidase (CD73) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Ecto-5'-nucleotidase (CD73) | Target's Patent Info | [1] | |
| BioCyc | Purine nucleotides degradation | |||
| Urate biosynthesis/inosine 5'-phosphate degradation | ||||
| Adenosine nucleotides degradation | ||||
| KEGG Pathway | Purine metabolism | |||
| Pyrimidine metabolism | ||||
| Nicotinate and nicotinamide metabolism | ||||
| Metabolic pathways | ||||
| Panther Pathway | Purine metabolism | |||
| Pyrimidine Metabolism | ||||
| Pathway Interaction Database | HIF-1-alpha transcription factor network | |||
| Reactome | Purine catabolism | |||
| WikiPathways | Differentiation Pathway | |||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | ||||
| miR-targeted genes in epithelium - TarBase | ||||
| Metabolism of nucleotides | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Ectonucleotidase inhibitors: a patent review (2011-2016).Expert Opin Ther Pat. 2017 Dec;27(12):1291-1304. | |||
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