Drug Information
Drug General Information | Top | |||
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Drug ID |
D04CLL
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Former ID |
DNC004698
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Drug Name |
3-[4-Methyl-indan-(1E)-ylidenemethyl]-pyridine
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Synonyms |
SCHEMBL4224799; BDBM8599; CHEMBL368305; SCHEMBL4224793; (3-Pyridylmethylene)indane 23a; AC1O7051; 3-[(E)-(4-methyl-2,3-dihydroinden-1-ylidene)methyl]pyridine
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C16H15N
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Canonical SMILES |
CC1=C2CCC(=CC3=CN=CC=C3)C2=CC=C1
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InChI |
1S/C16H15N/c1-12-4-2-6-16-14(7-8-15(12)16)10-13-5-3-9-17-11-13/h2-6,9-11H,7-8H2,1H3/b14-10+
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InChIKey |
ORCOWTSQEFCEFC-GXDHUFHOSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Aromatase (CYP19A1) | Target Info | Inhibitor | [1] |
Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] | |
BioCyc | Superpathway of steroid hormone biosynthesis | |||
Glucocorticoid biosynthesis | ||||
Mineralocorticoid biosynthesis | ||||
Estradiol biosynthesis II | ||||
Estradiol biosynthesis I | ||||
KEGG Pathway | Steroid hormone biosynthesis | |||
Metabolic pathways | ||||
Ovarian steroidogenesis | ||||
NetPath Pathway | FSH Signaling Pathway | |||
Panther Pathway | Androgen/estrogene/progesterone biosynthesis | |||
Pathwhiz Pathway | Steroidogenesis | |||
Androgen and Estrogen Metabolism | ||||
Reactome | Glucocorticoid biosynthesis | |||
Endogenous sterols | ||||
WikiPathways | Metapathway biotransformation | |||
Oxidation by Cytochrome P450 | ||||
Metabolism of steroid hormones and vitamin D | ||||
Corticotropin-releasing hormone | ||||
Tryptophan metabolism | ||||
Ovarian Infertility Genes | ||||
FSH signaling pathway | ||||
Integrated Breast Cancer Pathway | ||||
Phase 1 - Functionalization of compounds |
References | Top | |||
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REF 1 | Synthesis and evaluation of (pyridylmethylene)tetrahydronaphthalenes/-indanes and structurally modified derivatives: potent and selective inhibitor... J Med Chem. 2005 Mar 10;48(5):1563-75. |
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