Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04AIV
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| Former ID |
DNCL001575
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| Drug Name |
Eteplirsen
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| Synonyms |
AVI-4658
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| Indication | Duchenne dystrophy [ICD-11: 8C70; ICD-10: G71.0] | Approved | [1] | |
| Company |
Sarepta Therapeutics
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Dystrophin messenger RNA (DMD mRNA) | Target Info | Modulator | [1] |
| KEGG Pathway | Hypertrophic cardiomyopathy (HCM) | |||
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | ||||
| Dilated cardiomyopathy | ||||
| Viral myocarditis | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| IL5 Signaling Pathway | ||||
| Reactome | Non-integrin membrane-ECM interactions | |||
| Striated Muscle Contraction | ||||
| WikiPathways | Striated Muscle Contraction | |||
| Ectoderm Differentiation | ||||
| Extracellular matrix organization | ||||
| Arrhythmogenic Right Ventricular Cardiomyopathy | ||||
| Muscle contraction | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2016 FDA drug approvals. Nat Rev Drug Discov. 2017 Feb 2;16(2):73-76. | |||
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