Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03TCR
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| Drug Name |
PMID25522065-Compound-12
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| Drug Type |
Small molecular drug
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| Company |
ASTRAZENECA AB [SEASTRAZENECA UK LTD [GBBOEKMAN-WINIWARTER SUSANNE DORIS MARGIT [SEFREDENWALL MARLENE [SEHOGNER CARL ANDERS [SEJOHANSSON LARS ANDERS MIKAEL [SEJUDKINS ROBERT ANDREW [SELI LANNA [SELOEFBERG BJOERN CHRISTIAN INGVAR [SEUNGE SVERKER VON [SE]
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| Structure |
 |
Download2D MOL |
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| Formula |
C24H25ClN4O4
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| Canonical SMILES |
CC1=C(C=CC(=C1)CN2CCOCC2)OC3CN(C3)C(=O)C4=NN=C(O4)C5=CC=C(C=C5)Cl
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| InChI |
1S/C24H25ClN4O4/c1-16-12-17(13-28-8-10-31-11-9-28)2-7-21(16)32-20-14-29(15-20)24(30)23-27-26-22(33-23)18-3-5-19(25)6-4-18/h2-7,12,20H,8-11,13-15H2,1H3
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| InChIKey |
PGIWDCQJRFXKTN-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Melanin-concentrating hormone receptor 1 (MCHR1) | Target Info | Antagonist | [1] |
| Target's Patent Info | Melanin-concentrating hormone receptor 1 (MCHR1) | Target's Patent Info | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (q) signalling events | ||||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Novel MCH1 receptor antagonists: a patent review.Expert Opin Ther Pat. 2015 Feb;25(2):193-207. | |||
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