Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03RZM
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| Former ID |
DIB002462
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| Drug Name |
Steroid hormone conjugates
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| Synonyms |
AM-454; Steroid hormone conjugates (diabetes); DHEA-PC, AMUR; DHEA-PC, SuperGen; DHEA-phosphocoline, SuperGen; Steroid hormone conjugates (diabetes), SuperGen
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| Indication | Cachexia [ICD-11: MG20; ICD-10: R64; ICD-9: 799.4] | Terminated | [1] | |
| Company |
AMUR Pharmaceuticals Inc
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Estrogen-related receptor-alpha (ESRRA) | Target Info | Modulator | [2] |
| Reactome | PPARA activates gene expression | |||
| Transcriptional activation of mitochondrial biogenesis | ||||
| Nuclear Receptor transcription pathway | ||||
| WikiPathways | Mitochondrial Gene Expression | |||
| Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | ||||
| Nuclear Receptors | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015954) | |||
| REF 2 | The effect of six months treatment with a 100 mg daily dose of dehydroepiandrosterone (DHEA) on circulating sex steroids, body composition and muscle strength in age-advanced men and women. Clin Endocrinol (Oxf). 1998 Oct;49(4):421-32. | |||
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