Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03RDQ
|
|||
| Former ID |
DIB010135
|
|||
| Drug Name |
Gavilimomab
|
|||
| Synonyms |
ABX-CBL; CBL-1
Click to Show/Hide
|
|||
| Drug Type |
Antibody
|
|||
| Indication | Graft-versus-host disease [ICD-11: 4B24; ICD-9: 279.5] | Phase 2/3 | [1] | |
| Company |
Abgenix Inc
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Basigin (BSG) | Target Info | . | [2] |
| Pathway Interaction Database | Syndecan-1-mediated signaling events | |||
| Reactome | Degradation of the extracellular matrix | |||
| Basigin interactions | ||||
| Integrin cell surface interactions | ||||
| Pyruvate metabolism | ||||
| WikiPathways | The citric acid (TCA) cycle and respiratory electron transport | |||
| Integrin cell surface interactions | ||||
| Cell surface interactions at the vascular wall | ||||
| Matrix Metalloproteinases | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00035880) Study Comparing ABX-CBL (Monoclonal Antibody) Versus Atgam in Patients With Steroid Resistant Acute Graft Versus Host Disease. U.S. National Institutes of Health. | |||
| REF 2 | National Cancer Institute Drug Dictionary (drug id 38221). | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.