Drug Information
Drug General Information | Top | |||
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Drug ID |
D03PPZ
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Former ID |
DNC011244
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Drug Name |
Beta-Carboline-3-carboxylic acid t-butyl ester
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Drug Type |
Small molecular drug
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Structure |
Download2D MOL |
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Formula |
C16H16N2O2
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Canonical SMILES |
CC(C)(C)OC(=O)C1=NC=C2C(=C1)C3=CC=CC=C3N2
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InChI |
1S/C16H16N2O2/c1-16(2,3)20-15(19)13-8-11-10-6-4-5-7-12(10)18-14(11)9-17-13/h4-9,18H,1-3H3
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InChIKey |
FVFFDKKTXYVCCW-UHFFFAOYSA-N
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CAS Number |
CAS 93835-05-3
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
GABA(A) receptor alpha-2 (GABRA2) | Target Info | Inhibitor | [1] | |
GABA(A) receptor alpha-3 (GABRA3) | Target Info | Inhibitor | [1] | |
GABA(A) receptor alpha-5 (GABRA5) | Target Info | Inhibitor | [1] | |
GABA(A) receptor gamma-2 (GABRG2) | Target Info | Inhibitor | [1] | |
Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Retrograde endocannabinoid signaling | ||||
GABAergic synapse | ||||
Morphine addiction | ||||
Nicotine addiction | ||||
Reactome | Ligand-gated ion channel transport | |||
GABA A receptor activation | ||||
WikiPathways | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||
Iron uptake and transport | ||||
SIDS Susceptibility Pathways |
References | Top | |||
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REF 1 | Design, synthesis, and subtype selectivity of 3,6-disubstituted -carbolines at Bz/GABA(A)ergic receptors. SAR and studies directed toward agents f... Bioorg Med Chem. 2010 Nov 1;18(21):7548-64. |
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