Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03ONZ
|
|||
| Former ID |
DIB008942
|
|||
| Drug Name |
MCS-18
|
|||
| Synonyms |
Helleborus purpurascens-derived anti-inflammatory analgesic (injection, autoimmune disease), DoNatur
Click to Show/Hide
|
|||
| Indication | Autoimmune diabetes [ICD-11: 5A10] | Phase 2 | [1] | |
| Company |
DoNatur GmbH
|
|||
| Structure |
 |
Download2D MOL
|
||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Toll-like receptor 2 (TLR2) | Target Info | Modulator | [1] |
| KEGG Pathway | Phagosome | |||
| PI3K-Akt signaling pathway | ||||
| Toll-like receptor signaling pathway | ||||
| Legionellosis | ||||
| Leishmaniasis | ||||
| Chagas disease (American trypanosomiasis) | ||||
| Malaria | ||||
| Toxoplasmosis | ||||
| Amoebiasis | ||||
| Tuberculosis | ||||
| Hepatitis B | ||||
| Measles | ||||
| Herpes simplex infection | ||||
| Proteoglycans in cancer | ||||
| Inflammatory bowel disease (IBD) | ||||
| Rheumatoid arthritis | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| TCR Signaling Pathway | ||||
| Panther Pathway | Toll receptor signaling pathway | |||
| Pathway Interaction Database | Endogenous TLR signaling | |||
| Reactome | Beta defensins | |||
| MyD88:Mal cascade initiated on plasma membrane | ||||
| Toll Like Receptor TLR6:TLR2 Cascade | ||||
| MyD88 deficiency (TLR2/4) | ||||
| IRAK4 deficiency (TLR2/4) | ||||
| WikiPathways | Toll-like receptor signaling pathway | |||
| IL1 and megakaryotyces in obesity | ||||
| Human Complement System | ||||
| Toll-Like Receptors Cascades | ||||
| MyD88:Mal cascade initiated on plasma membrane | ||||
| Defensins | ||||
| Regulation of toll-like receptor signaling pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The novel arthritis-drug substance MCS-18 attenuates the antibody production in vivo. Acta Microbiol Immunol Hung. 2008 Mar;55(1):15-31. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.