Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03OCG
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| Former ID |
DIB011667
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| Drug Name |
FGF-21
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| Synonyms |
Fibroblast growth factor 21, Lilly; LP-10152; FGF-21, Lilly
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| Indication | Type-2 diabetes [ICD-11: 5A11; ICD-9: 250] | Discontinued in Phase 1/2 | [1] | |
| Company |
Eli Lilly & Co
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Fibroblast growth factor-21 (FGF21) | Target Info | Agonist | [2] |
| KEGG Pathway | MAPK signaling pathway | |||
| Ras signaling pathway | ||||
| Rap1 signaling pathway | ||||
| PI3K-Akt signaling pathway | ||||
| Regulation of actin cytoskeleton | ||||
| Pathways in cancer | ||||
| Melanoma | ||||
| Reactome | Facilitative Na+-independent glucose transporters | |||
| Glucose transport | ||||
| WikiPathways | Regulation of Actin Cytoskeleton | |||
| Aryl Hydrocarbon Receptor | ||||
| SREBP signalling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028644) | |||
| REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028644) | |||
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