Drug Information
Drug General Information | Top | |||
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Drug ID |
D03KQG
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Former ID |
DNC012069
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Drug Name |
Pyrrolidin-1-yl-thiourea
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Synonyms |
CHEMBL48338; 88147-87-9; N-Pyrrolidin-1-ylthiourea; Thiourea, 1-pyrrolidinyl-; SCHEMBL5320211; CTK3B7005; DTXSID20658163
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C5H11N3S
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Canonical SMILES |
C1CCN(C1)NC(=S)N
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InChI |
1S/C5H11N3S/c6-5(9)7-8-3-1-2-4-8/h1-4H2,(H3,6,7,9)
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InChIKey |
LUZJFNYVKQEEGM-UHFFFAOYSA-N
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CAS Number |
CAS 88147-87-9
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Transient receptor potential cation channel V1 (TRPV1) | Target Info | Inhibitor | [1] |
Transient receptor potential cation channel V4 (TRPV4) | Target Info | Inhibitor | [1] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Inflammatory mediator regulation of TRP channels | ||||
NetPath Pathway | IL2 Signaling Pathway | |||
Pathway Interaction Database | Trk receptor signaling mediated by the MAPK pathway | |||
Trk receptor signaling mediated by PI3K and PLC-gamma | ||||
Reactome | TRP channels |
References | Top | |||
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REF 1 | N-4-methansulfonamidobenzyl-N'-2-substituted-4-tert-butyl-benzyl thioureas as potent vanilloid receptor antagonistic ligands. Bioorg Med Chem Lett. 2004 Apr 5;14(7):1693-6. |
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