Drug Information

Drug General Information

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Drug ID

D03KQF

Former ID

DAP001150

Drug Name

Maprotiline

Synonyms

Deprilept; Dibencycladine; Maprotilin; Maprotilina; Maprotilinum; Maprotylina; Maprotylina [Polish]; TBB066626; BA-34276; Deprilept (TN); Ludiomil (TN); Maprotilina [INN-Spanish]; Maprotiline (USAN); Maprotilinum [INN-Latin]; Psymion (TN); Ba-34,276; Maprotiline [USAN:BAN:INN]; N-Methyl-9,10-ethanoanthracene-9(10H)-propanamine; N-Methyl-9,10-ethanoanthracene-9(10H)-propylamine; 3-(9,10-Dihydro-9,10-ethanoanthracen-9-yl)propylmethylamine; 3-(9,10-ethanoanthracen-9(10H)-yl)-N-methylpropan-1-amine

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Drug Type

Small molecular drug

Indication

Major depressive disorder [ICD-11: 6A70.3; ICD-10: F32.2]

Approved

[1]

Therapeutic Class

Antidepressants

Company

Norvatis Phamaceuticals Corporation

Structure

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2D MOL

3D MOL

Formula

C20H23N

Canonical SMILES

CNCCCC12CCC(C3=CC=CC=C31)C4=CC=CC=C24

InChI

1S/C20H23N/c1-21-14-6-12-20-13-11-15(16-7-2-4-9-18(16)20)17-8-3-5-10-19(17)20/h2-5,7-10,15,21H,6,11-14H2,1H3

InChIKey

QSLMDECMDJKHMQ-UHFFFAOYSA-N

CAS Number

CAS 10262-69-8

PubChem Compound ID

4011

PubChem Substance ID

9318, 5663164, 7849638, 7979861, 8152515, 10502561, 11111502, 11112599, 11113802, 11336066, 11361305, 11363781, 11366343, 11368905, 11371545, 11373608, 11377067, 11462277, 11466374, 11467494, 11483954, 11486068, 11487955, 11490299, 11491850, 11494701, 14775197, 17396737, 26751977, 28476385, 29223122, 46508358, 47211277, 47291194, 47589054, 47662343, 47662542, 47736549, 47811030, 47885658, 48035199, 48259301, 49699342, 49967387, 50085871, 50100934, 50104649, 57322094, 74719609, 85209857

ChEBI ID

CHEBI:6690

ADReCS Drug ID

BADD_D01350 ; BADD_D01351

SuperDrug ATC ID

N06AA21

SuperDrug CAS ID

cas=010262698

Target and Pathway

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Target(s)

Norepinephrine transporter (NET)