Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D03KKR
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| Former ID |
DNC000640
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| Drug Name |
Fasudil
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| Synonyms |
103745-39-7; HA1077; ha-1077; HA 1077; Fasudil [INN]; AT 877; Fasudilum [INN-Latin]; 1-(5-Isoquinolinesulfonyl)homopiperazine; 1H-1,4-Diazepine, hexahydro-1-(5-isoquinolinylsulfonyl)-; UNII-Q0CH43PGXS; 5-(1,4-diazepane-1-sulfonyl)isoquinoline; 5-(1,4-diazepan-1-ylsulfonyl)isoquinoline; (5-ISOQUINOLINESULFONYL)HOMOPIPERAZINE; AT-877; AT877; Q0CH43PGXS; 5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE; CHEMBL38380; Hexahydro-1-(5-isoquinolinylsulfonyl)-1H-1,4-diazepine; Fasudil (INN); Fasudilhydrochloride
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C14H17N3O2S
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| Canonical SMILES |
C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3
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| InChI |
1S/C14H17N3O2S/c18-20(19,17-9-2-6-15-8-10-17)14-4-1-3-12-11-16-7-5-13(12)14/h1,3-5,7,11,15H,2,6,8-10H2
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| InChIKey |
NGOGFTYYXHNFQH-UHFFFAOYSA-N
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| CAS Number |
CAS 103745-39-7
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| PubChem Compound ID | ||||
| PubChem Substance ID |
645246, 830160, 841200, 7411211, 7888736, 8152246, 11113364, 11121731, 11122211, 11362865, 11365427, 11367989, 11370941, 11370942, 11373590, 11376151, 14849184, 26751605, 26751606, 29222678, 46392968, 46394056, 46394198, 46514392, 47810568, 47959546, 48034909, 48110269, 48184808, 49961274, 50100814, 50871527, 53790340, 57321867, 81062559, 85787246, 85787262, 91614085, 92251456, 92308789, 92310082, 92708292, 93577882, 96024636, 99300994, 99302514, 99444633, 103064513, 103083244, 103210437
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| SuperDrug ATC ID |
C04AX32
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| SuperDrug CAS ID |
cas=103745397
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. | |||
| REF 2 | Long-term inhibition of Rho-kinase induces a regression of arteriosclerotic coronary lesions in a porcine model in vivo. Cardiovasc Res. 2001 Jul;51(1):169-77. | |||
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