Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03KIZ
|
|||
| Former ID |
DNCL002351
|
|||
| Drug Name |
RG7596
|
|||
| Indication | Haematological malignancy [ICD-11: 2B33.Y] | Phase 2 | [1] | |
| Company |
Genentech
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | B-cell-specific glycoprotein B29 (CD79B) | Target Info | Modulator | [2] |
| KEGG Pathway | B cell receptor signaling pathway | |||
| NetPath Pathway | IL4 Signaling Pathway | |||
| Leptin Signaling Pathway | ||||
| Panther Pathway | B cell activation | |||
| Pathway Interaction Database | BCR signaling pathway | |||
| Reactome | Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | |||
| WikiPathways | Signaling by the B Cell Receptor (BCR) | |||
| B Cell Receptor Signaling Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034127) | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2852). | |||
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