Drug Information
Drug General Information | Top | |||
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Drug ID |
D03KEK
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Former ID |
DAP001455
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Drug Name |
Artemisinin SP
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Synonyms |
Isoguvacine; isoguvacine; 1,2,3,6-tetrahydropyridine-4-carboxylic acid; 64603-90-3; 1,2,3,6-Tetrahydro-pyridine-4-carboxylic acid; 1,2,3,6-Tetrahydro-4-pyridinecarboxylic acid; UNII-YTF580771Y; CHEMBL39071; CHEBI:34799; YTF580771Y; 4-Pyridinecarboxylic acid, 1,2,3,6-tetrahydro-; AC1OEMUS; 1,2,3,6-tetrahydropyridinium-4-carboxylate; 1,2,3,6-tetrahydropyridin-1-ium-4-carboxylate; Tocris-0235; Spectrum_001974; Lopac-G-002; AC1L1GNT; Spectrum3_001869; Biomol-NT_000254; AC1Q5QG1; Lopac0_000561; KBioSS_002540; BSPBio_003318; DivK1c_000115
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Drug Type |
Small molecular drug
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Indication | Malaria [ICD-11: 1F40-1F45; ICD-10: B50-B64, B54] | Approved | [1] | |
Structure |
Download2D MOL |
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Formula |
C6H9NO2
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Canonical SMILES |
C1CNCC=C1C(=O)O
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InChI |
1S/C6H9NO2/c8-6(9)5-1-3-7-4-2-5/h1,7H,2-4H2,(H,8,9)
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InChIKey |
KRVDMABBKYMBHG-UHFFFAOYSA-N
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CAS Number |
CAS 64603-90-3
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PubChem Compound ID | ||||
PubChem Substance ID |
586283, 5272041, 7979656, 8152383, 11111207, 11113420, 11335290, 11360529, 11364940, 11367502, 11370064, 11372917, 11378235, 11461501, 11491684, 11495788, 12015356, 14916033, 26751658, 29222884, 47365033, 47440103, 47440104, 47662116, 47885261, 50031990, 50104353, 50923267, 57567230, 57641685, 87363507, 90340567, 103092093, 103156356, 103218918, 103941327, 104304454, 117541246, 124749811, 124880168, 124880169, 124880170, 125764028, 128425587, 132626133, 134224095, 134338654, 134340135, 135071814, 137103551
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ChEBI ID |
CHEBI:34799
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Target and Pathway | Top | |||
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Target(s) | Glutamate receptor AMPA (GRIA) | Target Info | Agonist | [2] |
Sarcoplasmic/endoplasmic reticulum calcium ATPase (ATP2A) | Target Info | Inhibitor | [1] |
References | Top | |||
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REF 1 | The fight against drug-resistant malaria: novel plasmodial targets and antimalarial drugs. Curr Med Chem. 2008;15(2):161-71. | |||
REF 2 | GABA(A) receptor ligands and their therapeutic potentials. Curr Top Med Chem. 2002 Aug;2(8):817-32. |
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