Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03JRO
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| Former ID |
DIB008870
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| Drug Name |
ADCI
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| Synonyms |
SBG-017
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| Drug Type |
Small molecular drug
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| Indication | Epileptic seizures [ICD-11: 8A61-8A6Z; ICD-9: 345.9, 780.3] | Phase 1 | [1] | |
| Company |
National Institutes of Health
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| Structure |
 |
Download2D MOL |
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| Formula |
C16H14N2O
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| Canonical SMILES |
C1C2C3=CC=CC=C3C(N2)(C4=CC=CC=C41)C(=O)N
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| InChI |
1S/C16H14N2O/c17-15(19)16-12-7-3-1-5-10(12)9-14(18-16)11-6-2-4-8-13(11)16/h1-8,14,18H,9H2,(H2,17,19)
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| InChIKey |
IFLVGRRVGPXYON-UHFFFAOYSA-N
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| CAS Number |
CAS 124070-15-1
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | N-methyl-D-aspartate receptor (NMDAR) | Target Info | Modulator | [1] |
| Sodium channel unspecific (NaC) | Target Info | Modulator | [1] | |
| KEGG Pathway | Dopaminergic synapse | |||
| Reactome | Interaction between L1 and Ankyrins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The anticonvulsant SGB-017 (ADCI) blocks voltage-gated sodium channels in rat and human neurons: comparison with carbamazepine. Epilepsia. 2000 Mar;41(3):263-70. | |||
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