Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03JJW
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| Drug Name |
PMID25522065-Compound-11
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| Drug Type |
Small molecular drug
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| Company |
ASTRAZENECA AB ASTRAZENECA UK LIMITED JOHANSSON, Lars, Anders, Mikael JUDKINS, Robert, Andrew LI, Lanna LOFBERG, Bjorn, Christian, Ingvar PERSSON, Joachim
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| Structure |
 |
Download2D MOL |
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| Formula |
C24H23ClN4O4
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| Canonical SMILES |
C1C(CN1C(=O)C2=NN=C(O2)C3=CC=C(C=C3)Cl)OC4=CC=C(C=C4)CN5CC6(C5)COC6
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| InChI |
1S/C24H23ClN4O4/c25-18-5-3-17(4-6-18)21-26-27-22(33-21)23(30)29-10-20(11-29)32-19-7-1-16(2-8-19)9-28-12-24(13-28)14-31-15-24/h1-8,20H,9-15H2
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| InChIKey |
OVCNWJXOBLGBEA-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Melanin-concentrating hormone receptor 1 (MCHR1) | Target Info | Antagonist | [1] |
| Target's Patent Info | Melanin-concentrating hormone receptor 1 (MCHR1) | Target's Patent Info | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (q) signalling events | ||||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Novel MCH1 receptor antagonists: a patent review.Expert Opin Ther Pat. 2015 Feb;25(2):193-207. | |||
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