Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D03IRR
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| Former ID |
DNC001118
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| Drug Name |
Phenazone
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| Synonyms |
antipyrine; Phenazone; 60-80-0; Antipyrin; Phenazon; Analgesine; Anodynine; Fenazone; Anodynin; Azophen; 2,3-Dimethyl-1-phenyl-5-pyrazolone; Antipirin; Phenozone; Methozin; Azophene; Phenylone; Pyrazophyl; Sedatine; Apirelina; Sedatin; Dimethyloxychinizin; Dimethyloxyquinazine; Phenazonum; Antipyrinum; Oxydimethylquinazine; Azophenum; Parodyne; Phenylon; Fenazona; 3-Antipyrine; Fenazon [Czech]; Auralgan; Fenazon; Fenazona [INN-Spanish]; Phenazone (pharmaceutical); 3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-2-phenyl-; Oxydimethylquinizine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C11H12N2O
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| Canonical SMILES |
CC1=CC(=O)N(N1C)C2=CC=CC=C2
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| InChI |
1S/C11H12N2O/c1-9-8-11(14)13(12(9)2)10-6-4-3-5-7-10/h3-8H,1-2H3
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| InChIKey |
VEQOALNAAJBPNY-UHFFFAOYSA-N
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| CAS Number |
CAS 60-80-0
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| PubChem Compound ID | ||||
| PubChem Substance ID |
73701, 585988, 609733, 897396, 3132034, 7548402, 7848839, 8149206, 8151497, 10321128, 10529438, 11112159, 11335659, 11360898, 11362852, 11365414, 11367976, 11371470, 11373763, 11376138, 11461870, 11466057, 11467177, 11483752, 11485754, 11487904, 11490121, 11491967, 11493872, 11533957, 14797281, 24846783, 24890859, 24891029, 26611611, 26679445, 26747866, 26747867, 26753718, 29221384, 32867460, 46505216, 47216735, 47291090, 47515275, 47662233, 47885364, 47959690, 48259186, 48414294
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| ChEBI ID |
CHEBI:31225
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| SuperDrug ATC ID |
N02BB01; S02DA03
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| SuperDrug CAS ID |
cas=000060800
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prostaglandin G/H synthase 1 (COX-1) | Target Info | Inhibitor | [1] |
| BioCyc | C20 prostanoid biosynthesis | |||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| Platelet activation | ||||
| Serotonergic synapse | ||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
| Panther Pathway | Inflammation mediated by chemokine and cytokine signaling pathway | |||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| WikiPathways | Prostaglandin Synthesis and Regulation | |||
| Arachidonic acid metabolism | ||||
| Phase 1 - Functionalization of compounds | ||||
| Eicosanoid Synthesis | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Pharmacokinetic and pharmacodynamic aspects of the ideal COX-2 inhibitor: a pharmacologist's perspective. Clin Exp Rheumatol. 2001 Nov-Dec;19(6 Suppl 25):S51-7. | |||
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