Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03BTP
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| Former ID |
DIB005184
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| Drug Name |
Fosfluridine tidoxil
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| Synonyms |
Fosfluridine; HDP-99-0006; 5-fluorouridine prodrug, Heidelberg Pharma
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| Drug Type |
Small molecular drug
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| Indication | Keratosis [ICD-11: ED56; ICD-10: L57.0] | Terminated | [1] | |
| Company |
Heidelberg Pharma Holding GmbH
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| Structure |
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Download2D MOL
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| Formula |
C34H62FN2O10PS
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| Canonical SMILES |
CCCCCCCCCCCCSCC(COP(=O)(O)OCC1C(C(C(O1)N2C=C(C(=O)NC2=O)F)O)O)OCCCCCCCCCC
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| InChI |
1S/C34H62FN2O10PS/c1-3-5-7-9-11-13-14-16-18-20-22-49-26-27(44-21-19-17-15-12-10-8-6-4-2)24-45-48(42,43)46-25-29-30(38)31(39)33(47-29)37-23-28(35)32(40)36-34(37)41/h23,27,29-31,33,38-39H,3-22,24-26H2,1-2H3,(H,42,43)(H,36,40,41)/t27?,29-,30-,31-,33-/m1/s1
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| InChIKey |
LBBDGLOPGRGFDO-FKJRLRTPSA-N
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| CAS Number |
CAS 174638-15-4
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019549) | |||
| REF 2 | Selective protection by uridine of growth inhibition by 5-fluorouracil (5FU) mediated by 5FU incorporation into RNA, but not the thymidylate synthase mediated growth inhibition by 5FU-leucovorin. Nucleosides Nucleotides Nucleic Acids. 2008 Jun;27(6):733-9. | |||
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