Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03AZU
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| Former ID |
DIB016114
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| Drug Name |
Org-31710
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| Synonyms |
Org-31806
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| Drug Type |
Small molecular drug
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| Indication | Contraception [ICD-11: QA21] | Discontinued in Phase 1 | [1] | |
| Company |
Organon BioSciences
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| Structure |
 |
Download2D MOL |
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| Formula |
C30H39NO2
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| Canonical SMILES |
CC1CC2C3CCC4(C3(CC(C2=C5C1=CC(=O)CC5)C6=CC=C(C=C6)N(C)C)C)CCCO4
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| InChI |
1S/C30H39NO2/c1-19-16-25-27-12-14-30(13-5-15-33-30)29(27,2)18-26(20-6-8-21(9-7-20)31(3)4)28(25)23-11-10-22(32)17-24(19)23/h6-9,17,19,25-27H,5,10-16,18H2,1-4H3/t19-,25+,26-,27+,29+,30+/m1/s1
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| InChIKey |
HFDGABTZPISMDD-IEVXGSBISA-N
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| CAS Number |
CAS 118968-41-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Progesterone receptor (PGR) | Target Info | Modulator | [2] |
| KEGG Pathway | Oocyte meiosis | |||
| Progesterone-mediated oocyte maturation | ||||
| Pathway Interaction Database | Cellular roles of Anthrax toxin | |||
| Reactome | Nuclear signaling by ERBB4 | |||
| Nuclear Receptor transcription pathway | ||||
| WikiPathways | Ovarian Infertility Genes | |||
| Signaling by ERBB4 | ||||
| Nuclear Receptors | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002550) | |||
| REF 2 | Progesterone receptor antagonists Org 31710 and RU 486 increase apoptosis in human periovulatory granulosa cells. Fertil Steril. 2001 Dec;76(6):1225-31. | |||
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