Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D03AJS
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| Former ID |
DNC008787
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| Drug Name |
SERGLIFLOZIN A
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| Synonyms |
SERGLIFLOZIN A; UNII-AR34521QFL; CHEMBL270766; AR34521QFL; O-glucoside, 4a; SCHEMBL2574820; BDBM20878; beta-D-Glucopyranoside, 2-((4-methoxyphenyl)methyl)phenyl; HFLCZNNDZKKXCS-OUUBHVDSSA-N; J3.551.075C; 2-(4-methoxybenzyl)phenyl betaD-glucopyranoside; 2-(4-methoxybenzyl)phenyl beta-D-glucopyranoside; 2-(4-methoxybenzyl)-phenyl beta-D-glucopyranoside; 2-(4-methoxy-benzyl)phenyl beta-D-glucopyranoside; (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-{2-[(4-methoxyphenyl)methyl]phenoxy}oxane-3,4,5-triol
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C20H24O7
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| Canonical SMILES |
COC1=CC=C(C=C1)CC2=CC=CC=C2OC3C(C(C(C(O3)CO)O)O)O
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| InChI |
1S/C20H24O7/c1-25-14-8-6-12(7-9-14)10-13-4-2-3-5-15(13)26-20-19(24)18(23)17(22)16(11-21)27-20/h2-9,16-24H,10-11H2,1H3/t16-,17-,18+,19-,20-/m1/s1
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| InChIKey |
HFLCZNNDZKKXCS-OUUBHVDSSA-N
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| CAS Number |
CAS 360775-96-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | SLC5A2 messenger RNA (SLC5A2 mRNA) | Target Info | Inhibitor | [1] |
| Reactome | Hexose transport | |||
| Na+-dependent glucose transporters | ||||
| Inositol transporters | ||||
| WikiPathways | NRF2 pathway | |||
| Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Novel C-aryl glucoside SGLT2 inhibitors as potential antidiabetic agents: 1,3,4-Thiadiazolylmethylphenyl glucoside congeners. Bioorg Med Chem. 2010 Mar 15;18(6):2178-2194. | |||
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