Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D02ZIO
|
|||
Former ID |
DNC009262
|
|||
Drug Name |
2,7-Bis[2-(butylamino)acetamido]anthraquinone
|
|||
Synonyms |
2,7-Bis[2-(butylamino)acetamido]anthraquinone; SCHEMBL4294896; CHEMBL494076
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C26H32N4O4
|
|||
Canonical SMILES |
CCCCNCC(=O)NC1=CC2=C(C=C1)C(=O)C3=C(C2=O)C=C(C=C3)NC(=O)CNCCCC
|
|||
InChI |
1S/C26H32N4O4/c1-3-5-11-27-15-23(31)29-17-7-9-19-21(13-17)26(34)22-14-18(8-10-20(22)25(19)33)30-24(32)16-28-12-6-4-2/h7-10,13-14,27-28H,3-6,11-12,15-16H2,1-2H3,(H,29,31)(H,30,32)
|
|||
InChIKey |
FYPZVYMKSUFNRS-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | TERT messenger RNA (TERT mRNA) | Target Info | Inhibitor | [1] |
KEGG Pathway | HTLV-I infection | |||
NetPath Pathway | IL2 Signaling Pathway | |||
Pathway Interaction Database | Validated targets of C-MYC transcriptional activation | |||
Regulation of Telomerase | ||||
IL2 signaling events mediated by PI3K | ||||
Regulation of nuclear beta catenin signaling and target gene transcription | ||||
HIF-1-alpha transcription factor network | ||||
Reactome | Formation of the beta-catenin:TCF transactivating complex | |||
WikiPathways | TGF beta Signaling Pathway | |||
miR-targeted genes in lymphocytes - TarBase | ||||
miR-targeted genes in epithelium - TarBase | ||||
Telomere Maintenance |
References | Top | |||
---|---|---|---|---|
REF 1 | Synthesis, human telomerase inhibition and anti-proliferative studies of a series of 2,7-bis-substituted amido-anthraquinone derivatives. Bioorg Med Chem. 2008 Jul 15;16(14):6976-86. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.