Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D02UKE
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| Former ID |
DNC014388
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| Drug Name |
5-(pyridin-4-yl)-1,3,4-thiadiazole-2(3H)-thione
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| Synonyms |
13581-25-4; 5-(pyridin-4-yl)-1,3,4-thiadiazole-2-thiol; CHEMBL596214; 5-(4-pyridyl)-1,3,4-thiadiazole-2-thiol; 5-(pyridin-4-yl)-1,3,4-thiadiazole-2(3H)-thione; 5-pyridin-4-yl-1,3,4-thiadiazole-2-thiol; 5-mercapto-2-(pyridin-4-yl)-1,3,4-thiadiazole; 1,3,4-Thiadiazole-2(3H)-thione, 5-(4-pyridinyl)-; AC1NRXV6; 5-pyridin-4-yl-3H-1,3,4-thiadiazole-2-thione; SCHEMBL969939; CTK0F4035; DTXSID70415420; MolPort-002-738-405; BDBM50304604; ZINC13532584; STK328652; AKOS030229631; AKOS005174322; MCULE-1265725983; KB-243965; R9200; ST45106367
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C7H5N3S2
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| Canonical SMILES |
C1=CN=CC=C1C2=NNC(=S)S2
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| InChI |
1S/C7H5N3S2/c11-7-10-9-6(12-7)5-1-3-8-4-2-5/h1-4H,(H,10,11)
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| InChIKey |
BSPHQWQMWIUIPM-UHFFFAOYSA-N
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| CAS Number |
CAS 13581-25-4
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [1] |
| BioCyc | (S)-reticuline biosynthesis | |||
| Eumelanin biosynthesis | ||||
| L-dopachrome biosynthesis | ||||
| KEGG Pathway | Tyrosine metabolism | |||
| Riboflavin metabolism | ||||
| Metabolic pathways | ||||
| Melanogenesis | ||||
| Pathwhiz Pathway | Riboflavin Metabolism | |||
| Tyrosine Metabolism | ||||
| WikiPathways | Dopamine metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | New potent inhibitors of tyrosinase: novel clues to binding of 1,3,4-thiadiazole-2(3H)-thiones, 1,3,4-oxadiazole-2(3H)-thiones, 4-amino-1,2,4-triaz... Bioorg Med Chem. 2010 Jun 1;18(11):4042-8. | |||
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