Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02TOI
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| Drug Name |
Tricyclic phytocannabinoid derivative 2
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| Synonyms |
PMID27215781-Compound-42
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| Drug Type |
Small molecular drug
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| Indication | Neuropathic pain [ICD-11: 8E43.0] | Patented | [1] | |
| Company |
NORTHEASTERN UNIVERSITY MAKRIYANNIS, Alexandros THAKUR, Ganesh, A. SHARMA, Rishi
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| Structure |
 |
Download2D MOL |
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| Formula |
C24H36O5
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| Canonical SMILES |
CCCCOC(=O)C(C)(C)C1=CC(=C2C3CC(CCC3C(OC2=C1)(C)C)CO)O
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| InChI |
1S/C24H36O5/c1-6-7-10-28-22(27)23(2,3)16-12-19(26)21-17-11-15(14-25)8-9-18(17)24(4,5)29-20(21)13-16/h12-13,15,17-18,25-26H,6-11,14H2,1-5H3/t15-,17-,18-/m1/s1
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| InChIKey |
OSVHLUXLWQLPIY-KBAYOESNSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cannabinoid receptor 1 (CB1) | Target Info | . | [1] |
| Cannabinoid receptor 2 (CB2) | Target Info | . | [1] | |
| Target's Patent Info | Cannabinoid receptor 1 (CB1) | Target's Patent Info | [1] | |
| Cannabinoid receptor 2 (CB2) | Target's Patent Info | [1] | ||
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Rap1 signaling pathway | ||||
| Retrograde endocannabinoid signaling | ||||
| Panther Pathway | Endogenous cannabinoid signaling | |||
| Pathway Interaction Database | N-cadherin signaling events | |||
| Reactome | Class A/1 (Rhodopsin-like receptors) | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Small Ligand GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| BDNF signaling pathway | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Cannabinoid receptor 2 (CB2) agonists and antagonists: a patent update.Expert Opin Ther Pat. 2016 Jul;26(7):843-56. | |||
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