Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02NYK
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| Former ID |
DIB014417
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| Drug Name |
Pifithrin-alpha
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| Synonyms |
P53 inhibitor, Univ of Illinois; PFT-alpha; PFT-beta; Pifithrin compounds, Quark; Pifithrin-beta
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| Drug Type |
Small molecular drug
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| Indication | Toxicity [ICD-11: N.A.] | Terminated | [1] | |
| Company |
University of Illinois
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| Structure |
 |
Download2D MOL |
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| Formula |
C16H19BrN2OS
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| Canonical SMILES |
CC1=CC=C(C=C1)C(=O)CN2C3=C(CCCC3)SC2=N.Br
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| InChI |
1S/C16H18N2OS.BrH/c1-11-6-8-12(9-7-11)14(19)10-18-13-4-2-3-5-15(13)20-16(18)17;/h6-9,17H,2-5,10H2,1H3;1H
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| InChIKey |
HAGVCKULCLQGRF-UHFFFAOYSA-N
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| CAS Number |
CAS 63208-82-2
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800012866) | |||
| REF 2 | An evaluation of the ability of pifithrin-alpha and -beta to inhibit p53 function in two wild-type p53 human tumor cell lines. Mol Cancer Ther. 2005 Sep;4(9):1369-77. | |||
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