Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02NEZ
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| Former ID |
DIB000275
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| Drug Name |
IMX-942
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| Synonyms |
IDR-1; IMX-001; IMX-502; IMX-502001; IMX-503; IMX-602; IMX-602001; IMX-606; IMX-606001; IMX-735; IMX-775; Innate immune system upregulators, Inimex; Innate defense-regulatory peptides (infection), Ininmex
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| Indication | Mucositis [ICD-11: CA00; ICD-10: J00] | Preclinical | [1] | |
| Company |
Inimex Pharmaceuticals Inc
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sequestosome-1 p62 (SQSTM1) | Target Info | Regulator (upregulator) | [2] |
| KEGG Pathway | Osteoclast differentiation | |||
| NetPath Pathway | EGFR1 Signaling Pathway | |||
| Pathway Interaction Database | IL1-mediated signaling events | |||
| TNF receptor signaling pathway | ||||
| p75(NTR)-mediated signaling | ||||
| Neurotrophic factor-mediated Trk receptor signaling | ||||
| Reactome | NRIF signals cell death from the nucleus | |||
| p75NTR recruits signalling complexes | ||||
| NF-kB is activated and signals survival | ||||
| Interleukin-1 signaling | ||||
| WikiPathways | Senescence and Autophagy in Cancer | |||
| NRF2 pathway | ||||
| Nuclear Receptors Meta-Pathway | ||||
| Apoptosis-related network due to altered Notch3 in ovarian cancer | ||||
| BDNF signaling pathway | ||||
| RANKL/RANK Signaling Pathway | ||||
| Signalling by NGF | ||||
| IL-1 signaling pathway | ||||
| Interleukin-1 signaling | ||||
| Regulation of toll-like receptor signaling pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018500) | |||
| REF 2 | Clinical pipeline report, company report or official report of SARomics Biostructures. | |||
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