Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02JWY
|
|||
| Former ID |
DNC014157
|
|||
| Drug Name |
SRI-224
|
|||
| Synonyms |
SRI-224; CHEMBL223505; [(E)-1-(4-methoxyphenyl)ethylideneamino]thiourea; p-Methoxyacetophenone thiosemicarbazone; 1-(4-methoxyphenyl)ethanone thiosemicarbazone; MolPort-000-248-698; ZINC15224175; BDBM50302754; AKOS000506378; p-methoxyphenyl(methyl)thiosemicarbazone; KB-89903; ST085316; BAS 00232870; 9P-047; SR-01000310617; [(E)-[1-(4-methoxyphenyl)ethylidene]amino]thiourea; SR-01000310617-1; (1E)-1-(4-methoxyphenyl)ethanone thiosemicarbazone
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C10H13N3OS
|
|||
| Canonical SMILES |
CC(=NNC(=S)N)C1=CC=C(C=C1)OC
|
|||
| InChI |
1S/C10H13N3OS/c1-7(12-13-10(11)15)8-3-5-9(14-2)6-4-8/h3-6H,1-2H3,(H3,11,13,15)/b12-7+
|
|||
| InChIKey |
JPXKIPVPEBSPLT-KPKJPENVSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [1] |
| BioCyc | (S)-reticuline biosynthesis | |||
| Eumelanin biosynthesis | ||||
| L-dopachrome biosynthesis | ||||
| KEGG Pathway | Tyrosine metabolism | |||
| Riboflavin metabolism | ||||
| Metabolic pathways | ||||
| Melanogenesis | ||||
| Pathwhiz Pathway | Riboflavin Metabolism | |||
| Tyrosine Metabolism | ||||
| WikiPathways | Dopamine metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Discovery of 4-functionalized phenyl-O-beta-D-glycosides as a new class of mushroom tyrosinase inhibitors. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6157-60. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.