Drug Information
Drug General Information | Top | |||
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Drug ID |
D02HRB
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Former ID |
DNC011678
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Drug Name |
RWJ-16979
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Canonical SMILES |
C1CN2C3=CC=CC=C3NC2=C(C1=O)C(=O)NC4=CC=CC=C4
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Retrograde endocannabinoid signaling | ||||
GABAergic synapse | ||||
Morphine addiction | ||||
Nicotine addiction | ||||
Reactome | Ligand-gated ion channel transport | |||
GABA A receptor activation | ||||
WikiPathways | SIDS Susceptibility Pathways | |||
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
Iron uptake and transport |
References | Top | |||
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REF 1 | Potential anxiolytic agents. Pyrido[1,2-a]benzimidazoles: a new structural class of ligands for the benzodiazepine binding site on GABA-A receptors. J Med Chem. 1995 Jan 6;38(1):16-20. |
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