Drug Information
Drug General Information | Top | |||
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Drug ID |
D02HMZ
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Former ID |
DNC011154
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Drug Name |
4-(2'-(trifluoromethoxy)biphenyl-3-yl)thiazole
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Synonyms |
CHEMBL1224656; BDBM50325809
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C16H10F3NOS
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Canonical SMILES |
C1=CC=C(C(=C1)C2=CC(=CC=C2)C3=CSC=N3)OC(F)(F)F
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InChI |
1S/C16H10F3NOS/c17-16(18,19)21-15-7-2-1-6-13(15)11-4-3-5-12(8-11)14-9-22-10-20-14/h1-10H
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InChIKey |
AJYWSJBYBSJCBJ-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Voltage-gated sodium channel alpha Nav1.7 (SCN9A) | Target Info | Inhibitor | [1] |
Reactome | Interaction between L1 and Ankyrins |
References | Top | |||
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REF 1 | Substituted biaryl oxazoles, imidazoles, and thiazoles as sodium channel blockers. Bioorg Med Chem Lett. 2010 Sep 15;20(18):5536-40. |
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