Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02FLB
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| Former ID |
DAP000128
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| Drug Name |
Sodium bicarbonate
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| Synonyms |
Acidosan; Colovage; Glycoprep; Golytely; Jusonin; Meylon; Natriumhydrogenkarbonat; Natron; Neut; Nulytely; Soludal; BSS plus; Baking soda; Bicarbonate of soda; Carbonic acid monosodium salt; Gripe water; Lithium bicarbonate; Monosodium hydrogen carbonate; Natrii hydrogencarbonas; Natrium bicarbonicum; Natrium hydrogencarbonicum; Natrum bicarbonicum; Sandoz sodium bicarbonate; Sel De vichy; Soda Mint; Sodium acid carbonate; Sodium bicarbonate in plastic container; Sodium bicarbonate liquid concentrate; Sodium bicarbonate solution; Sodium hydrocarbonate; Sodium hydrogen carbonate; Sodium hydrogencarbonate; NaHCO3; Bicarbonate, Sodium; Carbonic acid, monosodium salt; Co-lav; Col-evac; Go-evac; Hema BP-38; Hydrogen Carbonate, Sodium; Meylon (TN); Neut (TN); Peg-lyte; Soda (van); Soda, Baking; Sodium bicarbonate [USAN:JAN]; Carbonic acid sodium salt (1:1); E-Z-EM Prep Lyte; Sodium bicarbonate (1:1); Sodium bicarbonate (JP15/USP); Sodium carbonate (Na(HCO3)); 800 Sodium Bicarbonate Powder
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| Drug Type |
Small molecular drug
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| Indication | Metabolic acidosis [ICD-11: 5C73; ICD-10: E87.2; ICD-9: 276.2] | Approved | [1], [2], [3] | |
| Therapeutic Class |
Antidiarrheals
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| Structure |
 |
Download2D MOL |
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| Formula |
CHNaO3
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| Canonical SMILES |
C(=O)(O)[O-].[Na+]
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| InChI |
1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1
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| InChIKey |
UIIMBOGNXHQVGW-UHFFFAOYSA-M
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| CAS Number |
CAS 144-55-8
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| PubChem Compound ID | ||||
| PubChem Substance ID |
582993, 3133633, 4977523, 7848266, 8147837, 8669758, 10500654, 10501487, 11528438, 15296910, 24848145, 24858955, 24862462, 24865036, 24889074, 24899571, 24899582, 24899673, 24899682, 24899695, 24899739, 24899815, 24899817, 29227583, 46507049, 48414455, 48420011, 50755492, 50755494, 53787141, 57405912, 57647084, 57648561, 57654616, 103446806, 104042946, 109756634, 117376339, 124391975, 125307120, 125311860, 134337450, 134974257, 135091883, 135551762, 137001566, 140077586, 142262832, 143489532, 151975740
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| ChEBI ID |
CHEBI:32139
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| ADReCS Drug ID | BADD_D02034 | |||
| SuperDrug ATC ID |
B05CB04; B05XA02
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| SuperDrug CAS ID |
cas=000144558
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated calcium channel alpha Cav3.2 (CACNA1H) | Target Info | Blocker | [4] |
| Voltage-gated potassium channel Kv4.3 (KCND3) | Target Info | Blocker | [5] | |
| KEGG Pathway | MAPK signaling pathway | |||
| Calcium signaling pathway | ||||
| Circadian entrainment | ||||
| Pathwhiz Pathway | Muscle/Heart Contraction | |||
| Reactome | NCAM1 interactions | |||
| Voltage gated Potassium channels | ||||
| WikiPathways | Corticotropin-releasing hormone | |||
| NCAM signaling for neurite out-growth | ||||
| Potassium Channels | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4507). | |||
| REF 2 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 3 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 018509. | |||
| REF 4 | Acute renal failure. Clin Evid (Online). 2008 Sep 3;2008. pii: 2001. | |||
| REF 5 | Management of cocaine-induced cardiac arrhythmias due to cardiac ion channel dysfunction. Clin Toxicol (Phila). 2009 Jan;47(1):14-23. | |||
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