Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D02FCS
|
|||
Former ID |
DNC003621
|
|||
Drug Name |
15-nor-18-Methoxycornaridine
|
|||
Synonyms |
CHEMBL607096
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C21H26N2O3
|
|||
Canonical SMILES |
COCCC1C2CC3(C1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC
|
|||
InChI |
1S/C21H26N2O3/c1-25-10-8-14-13-11-21(20(24)26-2)18-16(7-9-23(12-13)19(14)21)15-5-3-4-6-17(15)22-18/h3-6,13-14,19,22H,7-12H2,1-2H3/t13?,14?,19-,21+/m0/s1
|
|||
InChIKey |
VNPGFSWKZRZJCI-XZKBRSTLSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Neuronal acetylcholine receptor beta-4 (CHRNB4) | Target Info | Inhibitor | [1] |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Cholinergic synapse | ||||
Panther Pathway | Nicotinic acetylcholine receptor signaling pathway | |||
Nicotine pharmacodynamics pathway | ||||
Reactome | Highly sodium permeable acetylcholine nicotinic receptors | |||
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors | ||||
Highly calcium permeable nicotinic acetylcholine receptors | ||||
WikiPathways | SIDS Susceptibility Pathways | |||
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
Nicotine Activity on Chromaffin Cells |
References | Top | |||
---|---|---|---|---|
REF 1 | Synthesis and biological evaluation of 18-methoxycoronaridine congeners. Potential antiaddiction agents. J Med Chem. 2003 Jun 19;46(13):2716-30. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.