Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02DVK
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| Former ID |
DIB001875
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| Drug Name |
CV-9201
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| Synonyms |
CV-9201-1; CV-9201-2; CV-9201-3; CV-9201-4; CV-9201-5; RNA-based vaccine (NY-ESO-1, MAGE-C1/CT7, MAGE-C2/CT10, NSCLC), CureVac
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| Drug Type |
Vaccine
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| Indication | Non-small-cell lung cancer [ICD-11: 2C25.Y] | Phase 1/2 | [1] | |
| Company |
CureVac GmbH
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Apoptosis inhibitor survivin (BIRC5) | Target Info | . | [2] |
| Cancer/testis antigen 1 (NY-ESO-1) | Target Info | . | [2] | |
| Cancer/testis antigen MAGE-C1/CT7 (MAGEC1) | Target Info | . | [3] | |
| Melanoma-associated antigen C2 (MAGEC2) | Target Info | . | [2] | |
| Oncotrophoblast glycoprotein 5T4 (TPBG) | Target Info | . | [2] | |
| KEGG Pathway | Hippo signaling pathway | |||
| Hepatitis B | ||||
| Pathways in cancer | ||||
| Colorectal cancer | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| Panther Pathway | Angiogenesis | |||
| Pathway Interaction Database | Aurora B signaling | |||
| Validated targets of C-MYC transcriptional activation | ||||
| FOXM1 transcription factor network | ||||
| Aurora A signaling | ||||
| Reactome | Separation of Sister Chromatids | |||
| Resolution of Sister Chromatid Cohesion | ||||
| RHO GTPases Activate Formins | ||||
| Mitotic Prometaphase | ||||
| WikiPathways | IL-4 Signaling Pathway | |||
| Apoptosis-related network due to altered Notch3 in ovarian cancer | ||||
| Mitotic Metaphase and Anaphase | ||||
| Mitotic Prometaphase | ||||
| Apoptosis | ||||
| Interleukin-11 Signaling Pathway | ||||
| Apoptosis Modulation and Signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00923312) Trial of an RNActive-Derived Cancer Vaccine in Stage IIIB/IV Non Small Cell Lung Cancer (NSCLC). U.S. National Institutes of Health. | |||
| REF 2 | National Cancer Institute Drug Dictionary (drug id 648549). | |||
| REF 3 | National Cancer Institute Drug Dictionary (drug id 648549). | |||
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