Drug Information
Drug General Information | Top | |||
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Drug ID |
D02BBN
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Former ID |
DNC014620
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Drug Name |
4-Amino-3-benzofuran-2-yl-butyric acid
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Synonyms |
121838-28-6; CHEMBL349520; 4-Amino-3-benzo(b)furan-2-ylbutanoic acid; 2-Benzofuranpropanoicacid, b-(aminomethyl)-; 4-amino-3-benzo[b]furan-2-ylbutanoic acid; Bfg-butanoic acid; 4-Amino-3-benzofuran-2-yl-butyric acid; ACMC-20mpq1; AC1L2VQL; 4-amino-3-(1-benzofuran-2-yl)butanoic acid; 2-Benzofuranpropanoic acid, beta-(aminomethyl)-; CTK4B2770; BDBM50021756; AKOS015439841; KB-240006
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C12H13NO3
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Canonical SMILES |
C1=CC=C2C(=C1)C=C(O2)C(CC(=O)O)CN
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InChI |
1S/C12H13NO3/c13-7-9(6-12(14)15)11-5-8-3-1-2-4-10(8)16-11/h1-5,9H,6-7,13H2,(H,14,15)
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InChIKey |
SRLRWPSSQWUHQC-UHFFFAOYSA-N
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CAS Number |
CAS 121838-28-6
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Gamma-aminobutyric acid B receptor (GABBR) | Target Info | Inhibitor | [1] |
KEGG Pathway | cAMP signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
GABAergic synapse | ||||
Estrogen signaling pathway | ||||
Morphine addiction | ||||
Reactome | Activation of G protein gated Potassium channels | |||
G alpha (i) signalling events | ||||
Class C/3 (Metabotropic glutamate/pheromone receptors) | ||||
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | ||||
WikiPathways | GPCRs, Class C Metabotropic glutamate, pheromone | |||
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
Potassium Channels | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | Synthesis and pharmacological evaluation of gamma-aminobutyric acid analogues. New ligand for GABAB sites. J Med Chem. 1987 Apr;30(4):743-6. |
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